Plant-Based Nutritional Supplementation Attenuates LPS-Induced Low-Grade Systemic Activation

41]. These factors control the transcription of inflammatory mediators, such as IL-1β, IL-6, TNF-α, TNF-β, INF-α, INFβ, INF-γnHighlight:Inflammation can alter insulin action and give rise to diabetes and obesity by blocking insulin receptor downstream events, impairing insulin receptor substrate 1 (IRS-1) activation and phosphatidylinositol 3-kinase-dependent (PI3K) pathways, therefore compromising insulin signalingnHighlight:systemic inflammation (generated by LPS) also increased neopterin levels in the urine and resulted in altered neuronal activity by decreasing dopamine (DA) metabolismnHighlight:Elevated levels of inflammatory mediators in the brain can alter neurogenesis, synaptic formation and neuronal sprouting, resulting in a decrease in cognitive abilitynHighlight:Diseases like Parkinson’s disease (PD), occur from the loss of dopamine producing neuronsnHighlight:an increase in neopterin levels has been recognized a sensitive biomarker for immune system activationnHighlight:Our experiments denoted that these diets were able to diminish inflammatory mediators and oxidative damagenHighlight:We established that diets enriched in phytochemicals limited the injury and improved behavioral outcomes in mice subjected to cerebral ischemic injuryn]]>

Picture of About Dr. Nathan Goodyear
About Dr. Nathan Goodyear

Dr. Nathan Goodyear, a medical doctor with years of experience in the field of integrative cancer care, has announced the launch of an online training program. This program, available on his new website, will provide individuals with access to video trainings led by Dr. Goodyear himself, covering a range of topics related to integrative cancer care. These trainings will include information on the latest research and techniques in the field, as well as guidance on how to incorporate these approaches into a patient’s overall cancer treatment plan. With this online program, Dr. Goodyear hopes to make his expertise and knowledge more widely accessible, and help more people understand the benefits of integrative cancer care.


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